Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992351 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HTTALOX15 | |
| SCHEMBL2996231 | 0.74 | DHPS (0.42) | MAPTALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL2997809 | 0.72 | HTT (0.46) | MAPTALDH1A1LMNAHTTPOLB | |
| SCHEMBL2998761 | 0.71 | DHPS (0.62) | MAPTALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL2998675 | 0.71 | HTT (0.49) | ALDH1A1HTTALOX15 | |
| SCHEMBL2995949 | 0.69 | HSD11B1 (0.40) | ALDH1A1L3MBTL1LMNAHTTFABP4 | |
| SCHEMBL3005941 | 0.68 | ALOX15 (0.41) | MAPTALDH1A1L3MBTL1LMNAHTT | |
| SCHEMBL569778 | 0.66 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1LMNALIG1 | |
| SCHEMBL31032281 | 0.66 | ALDH1A1 (0.47) | MAPTALDH1A1L3MBTL1LMNALIG1 | |
| SCHEMBL22312061 | 0.65 | TSHR (0.51) | MAPTALDH1A1TP53GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846112-A1 | BICYCLIC HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-10 | — | — | EP | disclosed |