Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL7144777 | 0.91 | MAPT (0.36) | KDM4EMAPTALDH1A1HTTPHGDH | |
| SCHEMBL8552648 | 0.86 | KDM4E (0.38) | KDM4EMAPTALDH1A1HTTPHGDH | |
| Trifluoromethanesulfonic Acid SCHEMBL8545942 | 0.78 | MGLL (0.36) | MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL8194433 | 0.69 | HSP90AA1 (0.40) | MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL8551417 | 0.69 | GPR183 (0.35) | KDM4EMAPTALDH1A1 | |
| Trifluoromethanesulfonic Acid SCHEMBL8189875 | 0.69 | HTR1F (0.56) | KDM4EMAPTALDH1A1HTTGAA | |
| SCHEMBL8552127 | 0.68 | KDM4E (0.39) | KDM4EMAPTALDH1A1GAARAD52 | |
| Trifluoromethanesulfonic Acid SCHEMBL8549018 | 0.67 | MAPT (0.34) | MAPTALDH1A1HTT | |
| SCHEMBL8547927 | 0.67 | ROCK1 (0.37) | KDM4EMAPTALDH1A1PHGDHGAA | |
| SCHEMBL8547854 | 0.66 | SMN1; SMN2 (0.45) | KDM4EMAPTALDH1A1HTTPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |