Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 3/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL8194433 | 0.90 | HSP90AA1 (0.40) | MGLLTP53MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL8549018 | 0.76 | MAPT (0.34) | MAPTUSP2MCHR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL7144777 | 0.69 | MAPT (0.36) | MAPT | |
| Trifluoromethanesulfonic Acid SCHEMBL7137485 | 0.65 | POLB (0.38) | — | |
| SCHEMBL8552648 | 0.64 | KDM4E (0.38) | TP53MAPTUSP2 | |
| SCHEMBL8931318 | 0.58 | ALDH1A1 (0.38) | MAPTUSP2 | |
| SCHEMBL2366564 | 0.56 | ALDH1A1 (0.63) | MGLLGPR183MAPTTSHRCYP3A4 | |
| SCHEMBL21485178 | 0.54 | HTR1A (0.75) | HTR1ADRD2HTR2A | |
| SCHEMBL13972823 | 0.54 | LMNA (0.64) | TP53MAPTUSP2TSHRCYP3A4 | |
| SCHEMBL32678152 | 0.54 | CYP1A2 (0.67) | GPR183TSHRCYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |