Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181951 | 0.87 | CNR1 (0.49) | CNR1CNR2ROCK2ROCK1MEN1 | |
| SCHEMBL8548044 | 0.85 | CNR1 (0.47) | CNR1CNR2ROCK2ROCK1MEN1 | |
| SCHEMBL8552802 | 0.84 | ROCK1 (0.41) | ROCK2ROCK1MEN1KMT2ANPC1 | |
| SCHEMBL8549181 | 0.82 | ROCK2 (0.42) | ROCK2ROCK1MEN1KMT2AHPGD | |
| SCHEMBL8550959 | 0.81 | KDM4E (0.39) | ROCK2ROCK1KMT2ANPC1RAB9A | |
| SCHEMBL22590401 | 0.74 | CNR1 (0.77) | CNR1CNR2ROCK2ROCK1MEN1 | |
| SCHEMBL5409240 | 0.73 | ROCK2 (0.67) | CNR1CNR2ROCK2ROCK1MEN1 | |
| SCHEMBL5418745 | 0.71 | ROCK2 (0.68) | ROCK2ROCK1MEN1KMT2ANPC1 | |
| SCHEMBL7138876 | 0.70 | HTR1F (0.45) | ROCK2ROCK1MEN1KMT2ANPC1 | |
| SCHEMBL23075124 | 0.70 | CNR1 (0.69) | CNR1CNR2ROCK2ROCK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |