Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 7/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 6/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138876 | 0.87 | HTR1F (0.45) | ROCK1ROCK2S1PR1MEN1KMT2A | |
| SCHEMBL8708225 | 0.85 | ROCK1 (0.41) | ROCK1ROCK2S1PR1MEN1KMT2A | |
| SCHEMBL8552248 | 0.84 | CNR1 (0.47) | ROCK1ROCK2S1PR1MEN1KMT2A | |
| SCHEMBL8546411 | 0.83 | ROCK2 (0.37) | ROCK1ROCK2MEN1KMT2ANPC1 | |
| SCHEMBL8550959 | 0.82 | KDM4E (0.39) | ROCK1ROCK2KMT2ANPC1RAB9A | |
| SCHEMBL8549181 | 0.81 | ROCK2 (0.42) | ROCK1ROCK2MEN1KMT2ADHODH | |
| SCHEMBL8551287 | 0.78 | HPGD (0.42) | ROCK2KMT2ANPC1RAB9A | |
| SCHEMBL8550329 | 0.73 | KDM4E (0.40) | ROCK1ROCK2 | |
| SCHEMBL7141367 | 0.72 | HTR1F (0.42) | ROCK1ROCK2MEN1KMT2ANPC1 | |
| SCHEMBL8181951 | 0.70 | CNR1 (0.49) | ROCK1ROCK2S1PR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |