Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 3/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | CTSA | P10619 | 6/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | OXGR1 | Q96P68 | 1/20 | 0.40 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553432 | 0.83 | CYP17A1 (0.55) | KCNA5FFAR1PDE4DCYP17A1ITGB3 | |
| SCHEMBL8555195 | 0.80 | KCNA5 (0.45) | SUCNR1KCNA5FFAR1CTSAPDE4D | |
| SCHEMBL8551198 | 0.76 | CYP3A4 (0.52) | PDE4DITGB3ITGAVITGA2B | |
| SCHEMBL8555025 | 0.74 | PDE4D (0.52) | FFAR1CTSAPDE4DCYP17A1ITGB3 | |
| Hydrochloric Acid SCHEMBL10664234 | 0.72 | KCNA5 (0.46) | SUCNR1KCNA5CYP17A1 | |
| SCHEMBL10919976 | 0.70 | CYP19A1 (0.50) | SUCNR1PDE4D | |
| Ammonia Solution, Strong SCHEMBL5999726 | 0.70 | KCNA5 (0.52) | KCNA5PDE4DTRPM8 | |
| SCHEMBL9519691 | 0.70 | L3MBTL1 (0.50) | KCNA5PDE4DITGB3ITGAVITGA2B | |
| SCHEMBL8553222 | 0.70 | PDE4D (0.49) | FFAR1PDE4D | |
| SCHEMBL8554087 | 0.70 | KCNA5 (0.46) | SUCNR1KCNA5FFAR1CTSAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |