Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550753 | 0.81 | TBXAS1 (0.45) | ADRB1ADRB3PDE4DALDH1A1HTT | |
| SCHEMBL8551240 | 0.75 | SMN1; SMN2 (0.44) | KCNA5ADRB1ADRB3ADRB2CYP17A1 | |
| SCHEMBL8555638 | 0.75 | SUCNR1 (0.43) | KCNA5KCNH2SUCNR1ADRB1ADRB3 | |
| SCHEMBL8478810 | 0.75 | MMP12 (0.48) | ADRB1ADRB3ADRB2KMOFYN | |
| SCHEMBL4426460 | 0.73 | KMO (0.73) | KMOFYNALDH1A1HTT | |
| SCHEMBL8555195 | 0.72 | KCNA5 (0.45) | KCNA5SUCNR1FFAR1CYP17A1PDE4D | |
| Hydrochloric Acid SCHEMBL8555644 | 0.70 | CYP3A4 (0.44) | KCNH2CYP17A1PDE4DLMNASMN1; SMN2 | |
| SCHEMBL8552254 | 0.70 | SUCNR1 (0.50) | KCNA5SUCNR1FFAR1CYP17A1PDE4D | |
| SCHEMBL8551012 | 0.69 | PDE4D (0.47) | KCNA5KCNH2CYP17A1PDE4DAKR1C3 | |
| SCHEMBL8551743 | 0.69 | KMO (0.51) | KCNA5KCNH2SUCNR1ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |