Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 8/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 5/20 | 0.53 |
| ▸ | DRD3 | P35462 | 5/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD5 | P21918 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552389 | 0.84 | ESR1 (0.46) | CHRM2CHRM1CHRM3 | |
| SCHEMBL27348016 | 0.81 | OPRK1 (0.56) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL8554273 | 0.77 | ESR1 (0.49) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7476970 | 0.77 | DRD2 (0.49) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| Butyl Formate SCHEMBL28975467 | 0.76 | DRD2 (0.48) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL18122716 | 0.73 | OPRK1 (0.91) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL29558042 | 0.72 | DRD2 (0.63) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL295433 | 0.72 | DRD2 (0.63) | OPRK1OPRM1OPRD1DRD2DRD3 | |
| SCHEMBL9080446 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL18122707 | 0.72 | OPRK1 (0.91) | OPRK1OPRM1OPRD1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |