Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.49 |
| ▸ | DRD3 | P35462 | 5/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 14/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4526988 | 0.83 | MAOA (0.42) | — | |
| SCHEMBL7463984 | 0.82 | ESRRG (0.43) | CHRM2CHRM1CHRM3 | |
| SCHEMBL6949347 | 0.82 | TAAR1 (0.44) | DRD3DRD1OPRM1CHRM2CHRM1 | |
| SCHEMBL27348016 | 0.79 | OPRK1 (0.56) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL8552295 | 0.77 | OPRK1 (0.53) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL7465544 | 0.74 | CALM1 (0.41) | CHRM2CHRM1CHRM3 | |
| SCHEMBL21810845 | 0.73 | DRD2 (0.50) | DRD2DRD3DRD1DRD4DRD5 | |
| SCHEMBL5741195 | 0.73 | ALDH1A1 (0.41) | — | |
| SCHEMBL6226054 | 0.73 | CYP1A2 (0.39) | — | |
| SCHEMBL4158364 | 0.72 | OPRK1 (0.55) | DRD2DRD3DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |