Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550182 | 0.86 | DRD2 (0.47) | DRD2SLC6A4 | |
| SCHEMBL8702974 | 0.86 | DRD2 (0.53) | DRD2SLC6A4 | |
| SCHEMBL8546639 | 0.85 | SMN1; SMN2 (0.48) | DRD2SLC6A4 | |
| SCHEMBL8548023 | 0.84 | DRD2 (0.50) | DRD2SLC6A4 | |
| SCHEMBL8552293 | 0.83 | LMNA (0.42) | DRD2SLC6A4 | |
| SCHEMBL8703834 | 0.83 | DRD2 (0.46) | DRD2SLC6A4 | |
| SCHEMBL8703019 | 0.83 | DRD2 (0.53) | DRD2SLC6A4 | |
| SCHEMBL8548938 | 0.83 | HTR1D (0.63) | DRD2SLC6A4 | |
| SCHEMBL8549540 | 0.83 | HTR1D (0.48) | DRD2SLC6A4 | |
| SCHEMBL8547499 | 0.82 | HTR1D (0.46) | DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |