SCHEMBL8552380

SCHEMBL8552380

CN(CCO)C(=O)c1ccccc1C(=O)N(C)CCO

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.52
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
PDK2 Q15119 1/20 0.43
HTR2C P28335 1/20 0.43
GAA P10253 2/20 0.42
TSHR P16473 2/20 0.42
CYP1A2 P05177 1/20 0.42
CDK4 P11802 3/20 0.41
CCND1 P24385 3/20 0.41
MAPT P10636 2/20 0.41
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.39
TACR1 P25103 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11208187 0.88 AKR1C3 (0.50) TP53KMT2AMEN1ALDH1A1HPGD
SCHEMBL27711150 0.87 KMT2A (0.51) TP53KMT2AMEN1ALDH1A1HPGD
SCHEMBL6552612 0.83 KMT2A (0.40) TP53KMT2AMEN1ALDH1A1HPGD
SCHEMBL1004454 0.82 KMT2A (0.51) KMT2AMEN1ALDH1A1HPGDPDK2
Hydrochloric Acid SCHEMBL27878081 0.80 KMT2A (0.50) KMT2AMEN1ALDH1A1HPGDPDK2
SCHEMBL12260918 0.79 MMP2 (0.50) TP53KMT2AMEN1ALDH1A1HPGD
SCHEMBL14095108 0.79 KEAP1 (0.68) TP53KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL4089780 0.78 TP53 (0.67) TP53KMT2AMEN1ALDH1A1SMN1; SMN2
SCHEMBL10795881 0.78 HDAC4 (0.54) ALDH1A1HPGDSMN1; SMN2PDK2CDK4
SCHEMBL30514751 0.78 KMT2A (0.59) TP53KMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5667842-A Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed