Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552661 | 0.81 | LMNA (0.37) | ALDH1A1LMNAMTNR1AMTNR1BPGR | |
| SCHEMBL7959053 | 0.75 | CYP1A2 (0.41) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL28040936 | 0.75 | CA1 (0.48) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL4639247 | 0.75 | MTNR1A (0.43) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL6923665 | 0.71 | CA1 (0.54) | KMT2AMEN1LMNACA1CA2 | |
| SCHEMBL10266885 | 0.71 | KMT2A (0.38) | KMT2AMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL5872309 | 0.70 | CYP1A2 (0.38) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL28941301 | 0.70 | CYP1A2 (0.33) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL28060320 | 0.70 | KDM4E (0.39) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 | |
| SCHEMBL18833426 | 0.70 | KDM4E (0.39) | CYP1A2CYP2C9CYP2C19KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |