Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552459 | 0.87 | CYP17A1 (0.44) | FFAR1ADRB3ADRB1PTAFRCYP17A1 | |
| SCHEMBL8552624 | 0.86 | CYP19A1 (0.47) | MKNK1MKNK2ADRB3ADRB1PSMB5 | |
| SCHEMBL8109544 | 0.86 | SMN1; SMN2 (0.44) | ADRB3ADRB1PSMB5KDM4ECYP17A1 | |
| SCHEMBL8118468 | 0.86 | KCNA5 (0.45) | FFAR1ADRB3ADRB1CYP17A1CYP19A1 | |
| SCHEMBL8123208 | 0.86 | MKNK1 (0.46) | FFAR1MKNK1MKNK2ADRB3ADRB1 | |
| SCHEMBL8118264 | 0.86 | DGAT2 (0.39) | FFAR1ADRB3ADRB1CYP17A1CYP19A1 | |
| SCHEMBL8118689 | 0.86 | KCNA5 (0.48) | PTAFRCASRCYP17A1CYP19A1CYP11B1 | |
| SCHEMBL8553727 | 0.85 | FFAR1 (0.47) | FFAR1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8117772 | 0.83 | KCNA5 (0.45) | HPGDKDM4ECYP17A1CYP19A1CYP11B1 | |
| SCHEMBL8672155 | 0.83 | KCNA5 (0.48) | FFAR1CYP17A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |