Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 9/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.41 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551073 | 0.89 | MAPK1 (0.47) | ALOX5GPR132MAPK1LMNASMN1; SMN2 | |
| SCHEMBL8550969 | 0.88 | EPHX1 (0.46) | HTTSMN1; SMN2CTSAEPHX1 | |
| SCHEMBL8109544 | 0.87 | SMN1; SMN2 (0.44) | HTTSMN1; SMN2 | |
| SCHEMBL8118689 | 0.86 | KCNA5 (0.48) | SMN1; SMN2 | |
| SCHEMBL8552479 | 0.85 | PRKCI (0.44) | FFAR1HPGDHTTSMN1; SMN2 | |
| SCHEMBL8552459 | 0.85 | CYP17A1 (0.44) | FFAR1 | |
| SCHEMBL8554677 | 0.82 | EPHX1 (0.42) | FFAR1LMNASMN1; SMN2EPHX1 | |
| SCHEMBL8552624 | 0.82 | CYP19A1 (0.47) | SMN1; SMN2 | |
| SCHEMBL8118468 | 0.82 | KCNA5 (0.45) | FFAR1 | |
| SCHEMBL8118264 | 0.82 | DGAT2 (0.39) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |