Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.37 |
| ▸ | FEN1 | P39748 | 2/20 | 0.37 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553275 | 0.88 | GRM5 (0.41) | TRPV1KIF11CTSSCTSKKDR | |
| SCHEMBL8552904 | 0.86 | TRPV1 (0.39) | TRPV1KIF11CTSSCTSKKDR | |
| SCHEMBL8552758 | 0.85 | KIF11 (0.42) | TRPV1KIF11CTSSCTSKSCN9A | |
| SCHEMBL8548872 | 0.83 | POLB (0.43) | TRPV1KIF11CTSSCTSKKDM4E | |
| SCHEMBL8549675 | 0.81 | ADORA1 (0.46) | TRPV1KIF11CTSSCTSKSCN9A | |
| SCHEMBL8550852 | 0.79 | KIF11 (0.39) | TRPV1KIF11CTSSCTSKSCN9A | |
| SCHEMBL8552573 | 0.78 | TRPV1 (0.37) | TRPV1KIF11CTSSCTSKSCN9A | |
| SCHEMBL16013131 | 0.77 | CTSS (0.49) | KIF11CTSSCTSKKDM4ESMN1; SMN2 | |
| SCHEMBL8546808 | 0.77 | POLB (0.43) | KIF11CTSSCTSKKDM4ELMNA | |
| SCHEMBL8549067 | 0.77 | CTSS (0.45) | CTSSCTSKKDM4ESCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | claimed |
| EP-0820996-A1 | Herbicidal cyanopyridines | American Cyanamid Company (US) | 1998-01-28 | — | — | EP | disclosed |