Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.66 |
| ▸ | CES1 | P23141 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.45 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552684 | 0.86 | CES2 (0.66) | CES2CES1ALDH1A1KDM4EGAA | |
| SCHEMBL24054956 | 0.86 | CES2 (0.54) | CES2CES1ALDH1A1KDM4EGAA | |
| SCHEMBL11281143 | 0.83 | CES2 (0.67) | CES2CES1ALDH1A1LMNANPC1 | |
| SCHEMBL812736 | 0.82 | LMNA (0.67) | CES2CES1ALDH1A1KDM4EGAA | |
| SCHEMBL29262742 | 0.82 | LMNA (0.67) | CES2CES1ALDH1A1KDM4EGAA | |
| SCHEMBL18438932 | 0.82 | CES2 (0.84) | CES2CES1ALDH1A1KDM4EGAA | |
| SCHEMBL11279596 | 0.80 | ALDH1A1 (0.68) | CES2CES1ALDH1A1KDM4ELMNA | |
| SCHEMBL11382156 | 0.80 | CES2 (1.00) | CES2CES1ALDH1A1GAALMNA | |
| SCHEMBL68736 | 0.80 | CES2 (0.55) | CES2CES1ALDH1A1KDM4ELMNA | |
| Methoxymethane SCHEMBL36596 | 0.78 | CES2 (0.53) | CES2CES1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |