Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551920 | 0.86 | ATM (0.46) | ATMLMNAPOLBMAPTALDH1A1 | |
| SCHEMBL7144550 | 0.85 | ATM (0.46) | ATMLMNAPOLBMAPTALDH1A1 | |
| SCHEMBL6668295 | 0.77 | HTR1F (0.44) | ATMLMNAPOLBALDH1A1KDM4E | |
| SCHEMBL7146399 | 0.66 | HTR1F (0.61) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8552249 | 0.63 | F2R (0.43) | LMNAPOLBMAPTALDH1A1KDM4E | |
| SCHEMBL8551467 | 0.63 | GRM5 (0.36) | LMNAMAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL3118074 | 0.62 | HTT (0.60) | ATMLMNAMAPTALDH1A1KDM4E | |
| Malonic Acid SCHEMBL8548925 | 0.62 | HTR1F (0.47) | MAPTALDH1A1KDM4ESMN1; SMN2TP53 | |
| SCHEMBL18073562 | 0.61 | MEN1 (0.62) | ATMLMNAMAPTALDH1A1KDM4E | |
| SCHEMBL3123474 | 0.61 | KDR (0.64) | ATMMAPTALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |