Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552887 | 0.88 | NR4A2 (0.47) | RXRARXRBRXRGNR4A2KMT2A | |
| SCHEMBL8557576 | 0.83 | MEN1 (0.52) | RXRARXRBKMT2AKCNH2DRD4 | |
| SCHEMBL8553475 | 0.83 | GAA (0.45) | RXRARXRBKMT2AKCNH2DRD4 | |
| SCHEMBL8557330 | 0.81 | CETP (0.43) | RXRARXRBRXRGKMT2AKCNH2 | |
| Hydrochloric Acid SCHEMBL8554703 | 0.81 | GAA (0.43) | RXRARXRBKMT2AKCNH2DRD4 | |
| SCHEMBL8554568 | 0.80 | KDR (0.58) | RXRARXRBRXRGNR4A2KMT2A | |
| SCHEMBL8555057 | 0.79 | NR4A2 (0.51) | RXRARXRBRXRGNR4A2KMT2A | |
| SCHEMBL8553599 | 0.77 | KDR (0.48) | RXRARXRBRXRGNR4A2KMT2A | |
| SCHEMBL8558360 | 0.76 | RXRA (0.50) | RXRARXRBRXRGNR4A2KMT2A | |
| SCHEMBL8555039 | 0.76 | ATM (0.62) | RXRARXRBRXRGKMT2AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |