Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9041732 | 0.86 | GRIN1 (0.38) | KDM4ETDP1USP2POLBRORA | |
| SCHEMBL8557499 | 0.78 | PDE5A (0.46) | ALDH1A1MEN1PMP22KMT2AHPGD | |
| SCHEMBL9044930 | 0.76 | PGR (0.35) | KDM4ETDP1ALDH1A1ADRB2ADRA2A | |
| SCHEMBL9041875 | 0.71 | PDE2A (0.34) | MAT2AMAOB | |
| SCHEMBL8555347 | 0.69 | PDE5A (0.41) | ALDH1A1MEN1PMP22KMT2AUSP2 | |
| SCHEMBL15473611 | 0.66 | ALDH1A1 (0.47) | SRCKDM4EKMOALDH1A1MEN1 | |
| SCHEMBL11086547 | 0.65 | GABRA5 (0.49) | KDM4EALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL11343226 | 0.63 | PFKFB3 (0.44) | KDM4EALDH1A1USP2HPGDCYP2C19 | |
| SCHEMBL8557963 | 0.63 | GRIN2D (0.40) | — | |
| SCHEMBL10745368 | 0.63 | CYP1A2 (0.40) | ALDH1A1MEN1PMP22KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |