Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | PDE9A | O76083 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555347 | 0.88 | PDE5A (0.41) | PDE5APDE9AMEN1CYP1A2KMT2A | |
| SCHEMBL8557963 | 0.81 | GRIN2D (0.40) | EGLN1 | |
| SCHEMBL9043231 | 0.80 | POLB (0.48) | MEN1KMT2AMAPTNPSR1ALDH1A1 | |
| SCHEMBL7773136 | 0.78 | GRIA1 (0.51) | — | |
| SCHEMBL8552970 | 0.78 | SRC (0.35) | MEN1KMT2ACYP2C19PMP22ALDH1A1 | |
| SCHEMBL8557418 | 0.76 | PDE5A (0.49) | PDE5APDE9AMEN1CYP1A2KMT2A | |
| SCHEMBL8557792 | 0.74 | PDE5A (0.47) | PDE5APDE9AMEN1CYP1A2KMT2A | |
| SCHEMBL8557015 | 0.74 | PDE9A (0.47) | PDE5APDE9AMEN1CYP1A2KMT2A | |
| SCHEMBL31328139 | 0.72 | PDE5A (0.52) | PDE5APDE9AMEN1CYP1A2KMT2A | |
| SCHEMBL7505355 | 0.72 | PDE5A (0.52) | PDE5APDE9AMEN1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |