Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548460 | 0.86 | NPSR1 (0.62) | NPSR1ATMROCK1KDM4EALDH1A1 | |
| SCHEMBL8552572 | 0.85 | ALDH1A1 (0.48) | NPSR1ATMROCK1KDM4EALDH1A1 | |
| SCHEMBL8552195 | 0.80 | AR (0.42) | NPSR1ATMPDPK1LMNAROCK1 | |
| SCHEMBL31014288 | 0.78 | ATM (0.73) | NPSR1ATMLMNAROCK1KDM4E | |
| SCHEMBL706420 | 0.78 | ATM (0.73) | NPSR1ATMLMNAROCK1KDM4E | |
| SCHEMBL8550946 | 0.77 | ADORA2A (0.41) | NPSR1ATMKDM4EALDH1A1MAPT | |
| SCHEMBL8547990 | 0.77 | NPSR1 (0.50) | NPSR1ATMPDPK1LMNAROCK1 | |
| SCHEMBL8551285 | 0.74 | AR (0.42) | NPSR1ATMPDPK1LMNAROCK1 | |
| SCHEMBL8551565 | 0.74 | KMT2A (0.42) | NPSR1LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL8551583 | 0.74 | NPSR1 (0.62) | NPSR1ATMROCK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |