Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549262 | 0.89 | ALDH1A1 (0.41) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8551877 | 0.88 | ESR1 (0.37) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8552712 | 0.79 | ENPP1 (0.38) | CYP2C9CYP2C19CYP3A4GAAADORA2A | |
| SCHEMBL8549556 | 0.78 | PLAU (0.44) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8546655 | 0.77 | MAPK1 (0.42) | KMT2ACYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL8549331 | 0.76 | HSD11B1 (0.42) | KMT2ACYP1A2ALDH1A1HPGDNPC1 | |
| SCHEMBL8549550 | 0.76 | KDR (0.44) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31359722 | 0.75 | KMT2A (0.57) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1396090 | 0.75 | KMT2A (0.57) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8553016 | 0.74 | NPSR1 (0.45) | KMT2AMEN1ALDH1A1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |