Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SHMT1 | P34896 | 3/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556781 | 1.00 | KDM4E (0.40) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL8553030 | 0.85 | THRB (0.42) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8553036 | 0.85 | THRB (0.42) | KDM4ESMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL8553904 | 0.81 | THRB (0.40) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL8555297 | 0.76 | THRB (0.43) | MAPTTP53 | |
| SCHEMBL8554248 | 0.73 | MAPT (0.43) | KDM4EMAPTPOLBTP53LMNA | |
| SCHEMBL8552141 | 0.72 | MAPK1 (0.31) | — | |
| SCHEMBL8552144 | 0.72 | MAPK1 (0.31) | — | |
| SCHEMBL9709798 | 0.67 | PRKD3 (0.40) | KDM4ESMN1; SMN2NPC1CRHBPRAB9A | |
| SCHEMBL7944695 | 0.67 | TSHR (0.53) | KDM4ESMN1; SMN2NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | claimed |