Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 4/20 | 0.38 |
| ▸ | FLT4 | P35916 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553758 | 0.82 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL1984012 | 0.81 | NTRK1 (0.48) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8554531 | 0.81 | MAPT (0.43) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8552593 | 0.79 | MAPT (0.41) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8555738 | 0.79 | TDP1 (0.44) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8553207 | 0.78 | P2RY12 (0.42) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8554113 | 0.78 | FPR1 (0.47) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8551950 | 0.74 | STS (0.39) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL8550650 | 0.72 | FPR1 (0.53) | ALDH1A1LMNA | |
| SCHEMBL8552895 | 0.71 | FPR1 (0.48) | ALDH1A1SMN1; SMN2NPSR1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |