Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 11/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555862 | 0.92 | NTRK1 (0.48) | FPR1LMNASLCO1B1NTRK1GAA | |
| SCHEMBL1984012 | 0.92 | NTRK1 (0.48) | FPR1LMNASLCO1B1NTRK1L3MBTL1 | |
| SCHEMBL8552895 | 0.90 | FPR1 (0.48) | FPR1LMNASLCO1B1NTRK1GAA | |
| SCHEMBL8553012 | 0.89 | LMNA (0.49) | FPR1LMNASLCO1B1GAAL3MBTL1 | |
| SCHEMBL8555343 | 0.88 | FPR1 (0.50) | FPR1LMNASLCO1B1NTRK1GAA | |
| SCHEMBL8556018 | 0.88 | LMNA (0.48) | FPR1LMNASLCO1B1NTRK1GAA | |
| SCHEMBL8555845 | 0.87 | LMNA (0.47) | FPR1LMNASLCO1B1NTRK1GAA | |
| SCHEMBL8555582 | 0.87 | LMNA (0.47) | FPR1LMNASLCO1B1NTRK1GAA | |
| SCHEMBL8551653 | 0.86 | NTRK1 (0.53) | FPR1LMNANTRK1POLBHTT | |
| SCHEMBL8557247 | 0.85 | NTRK1 (0.51) | FPR1SLCO1B1NTRK1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |