Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 7/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.37 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.37 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553207 | 0.89 | P2RY12 (0.42) | FPR1P2RY12ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8553758 | 0.79 | ALDH1A1 (0.46) | FPR1P2RY12ALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL8553085 | 0.78 | ALDH1A1 (0.43) | P2RY12ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL1984012 | 0.77 | NTRK1 (0.48) | FPR1ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL8554531 | 0.77 | MAPT (0.43) | P2RY12ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL8555738 | 0.75 | TDP1 (0.44) | P2RY12ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL8552593 | 0.75 | MAPT (0.41) | P2RY12ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL8551950 | 0.70 | STS (0.39) | P2RY12ALDH1A1SMN1; SMN2CA12CA1 | |
| SCHEMBL8556246 | 0.69 | KCNJ6 (0.55) | KCNJ6KCNJ5KCNJ3 | |
| SCHEMBL8550650 | 0.69 | FPR1 (0.53) | FPR1ALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | claimed |
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |