Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 6/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556961 | 0.91 | MAPT (0.45) | SMN1; SMN2NPC1RAB9APOLBRXFP1 | |
| SCHEMBL8557773 | 0.82 | POLB (0.48) | NPC1RAB9APOLBRXFP1HPGD | |
| SCHEMBL8557547 | 0.79 | TP53 (0.51) | NPC1RAB9ARXFP1HPGDMAPT | |
| SCHEMBL8556217 | 0.79 | MAPK9 (0.41) | SMN1; SMN2KDM4EALDH1A1MAPTTP53 | |
| SCHEMBL8556456 | 0.76 | TP53 (0.36) | HPGDMAPTTP53 | |
| SCHEMBL8556454 | 0.76 | TP53 (0.36) | HPGDMAPTTP53 | |
| SCHEMBL8554965 | 0.75 | TP53 (0.34) | MAPTTP53 | |
| SCHEMBL8554499 | 0.74 | TP53 (0.57) | NPC1RAB9AMAPTTP53LMNA | |
| SCHEMBL8556548 | 0.74 | THRB (0.53) | MAPTTP53 | |
| SCHEMBL8556432 | 0.74 | TP53 (0.47) | RXFP1MAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0554957-B1 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINI RICERCA SCIENT TECNOLOG (IT) | 1998-04-15 | — | — | EP | disclosed |
| US-5334609-A | Used in agriculture | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-08-02 | — | — | US | disclosed |
| EP-0554957-A2 | Thiazole derivatives of alkoxyacrylates with a fungicidal activity | MINISTERO DELL' UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECNOLOGICA (IT) | 1993-08-11 | — | — | EP | disclosed |