Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553136 | 0.91 | SMN1; SMN2 (0.41) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8557773 | 0.87 | POLB (0.48) | MAPTNPC1RAB9AMRGPRX4HPGD | |
| SCHEMBL8556548 | 0.82 | THRB (0.53) | MAPTTP53THRB | |
| SCHEMBL8553904 | 0.77 | THRB (0.40) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL8556217 | 0.77 | MAPK9 (0.41) | MAPTSMN1; SMN2TP53ALDH1A1KDM4E | |
| SCHEMBL8554723 | 0.74 | TP53 (0.50) | MAPTNPC1RAB9AHPGDTP53 | |
| SCHEMBL8556454 | 0.74 | TP53 (0.36) | MAPTHPGDTP53 | |
| SCHEMBL8556456 | 0.74 | TP53 (0.36) | MAPTHPGDTP53 | |
| SCHEMBL8554965 | 0.73 | TP53 (0.34) | MAPTTP53 | |
| SCHEMBL8557547 | 0.73 | TP53 (0.51) | MAPTNPC1RAB9AHPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454511-B1 | N-substituted heterocycle derivatives, their preparation, compositions containing them | SANOFI SA (FR) | 1998-06-17 | — | — | EP | disclosed |
| US-5334609-A | Used in agriculture | MINISTERO DELL'UNIVERSITA' E DELLA RICERCA SCIENTIFICA E TECHNOLOGICA (IT) | 1994-08-02 | — | — | US | disclosed |