Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | CBX7 | O95931 | 1/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755818 | 0.86 | SCN9A (0.56) | L3MBTL1SCN9ANR3C1BRD4 | |
| SCHEMBL4675455 | 0.79 | HTR6 (0.69) | BRD4 | |
| SCHEMBL8554874 | 0.78 | USP2 (0.63) | L3MBTL1TSHRMAPTKDM4EALDH1A1 | |
| SCHEMBL8556616 | 0.73 | TSHR (0.65) | L3MBTL1TSHRMAPTALDH1A1POLB | |
| SCHEMBL2271019 | 0.72 | SCN9A (0.60) | MAPTSCN9AKDM4EALDH1A1ALOX12 | |
| SCHEMBL26711297 | 0.72 | GSK3A (0.57) | TSHRALDH1A1NR3C1POLBKMT2A | |
| SCHEMBL31667554 | 0.71 | L3MBTL1 (0.70) | L3MBTL1TSHRMAPTALDH1A1TP53 | |
| SCHEMBL2309564 | 0.71 | SCN9A (0.54) | SCN9A | |
| SCHEMBL8554715 | 0.71 | L3MBTL1 (1.00) | L3MBTL1TSHRMAPTALDH1A1TP53 | |
| SCHEMBL474614 | 0.70 | TSHR (0.60) | L3MBTL1TSHRALDH1A1ALOX12TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |