Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | GRM5 | P41594 | 2/20 | 0.61 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556616 | 0.89 | TSHR (0.65) | USP2TSHRL3MBTL1CYP1A2GAA | |
| SCHEMBL8552768 | 0.86 | BRD4 (0.61) | USP2TSHRL3MBTL1CYP1A2GAA | |
| SCHEMBL27377932 | 0.85 | CYP1A2 (0.51) | USP2TSHRL3MBTL1CYP1A2GAA | |
| SCHEMBL27377925 | 0.81 | SLC5A1 (0.48) | USP2TSHRL3MBTL1CYP1A2GAA | |
| SCHEMBL29790799 | 0.80 | MAPT (0.54) | USP2KMT2AMEN1LMNAMAPT | |
| SCHEMBL18581261 | 0.80 | MAPT (0.54) | USP2KMT2AMEN1LMNAMAPT | |
| SCHEMBL31667554 | 0.80 | L3MBTL1 (0.70) | USP2TSHRL3MBTL1GAADRD4 | |
| SCHEMBL8556518 | 0.80 | TSHR (0.60) | USP2TSHRL3MBTL1GRM5DRD4 | |
| SCHEMBL12107887 | 0.79 | CYP2C9 (0.53) | USP2CYP1A2GAACYP2C9CYP2C19 | |
| SCHEMBL8553180 | 0.78 | L3MBTL1 (0.55) | TSHRL3MBTL1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |