Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GRM5 | P41594 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CBX7 | O95931 | 1/20 | 0.48 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.48 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554874 | 0.89 | USP2 (0.63) | TSHRL3MBTL1DRD4USP2GRM5 | |
| SCHEMBL31667554 | 0.82 | L3MBTL1 (0.70) | TSHRL3MBTL1DRD4USP2KMT2A | |
| SCHEMBL8556518 | 0.82 | TSHR (0.60) | TSHRL3MBTL1DRD4USP2GRM5 | |
| SCHEMBL4506469 | 0.78 | ALDH1A1 (0.69) | TSHRL3MBTL1DRD4USP2KMT2A | |
| SCHEMBL8554715 | 0.78 | L3MBTL1 (1.00) | TSHRL3MBTL1DRD4KMT2AMEN1 | |
| SCHEMBL13973048 | 0.78 | SLC5A1 (0.45) | TSHRL3MBTL1DRD4USP2KMT2A | |
| SCHEMBL8553880 | 0.77 | L3MBTL1 (0.64) | TSHRL3MBTL1DRD4USP2KMT2A | |
| SCHEMBL18581120 | 0.77 | MAPT (0.52) | TSHRUSP2KMT2AMEN1LMNA | |
| SCHEMBL29790744 | 0.77 | MAPT (0.52) | TSHRUSP2KMT2AMEN1LMNA | |
| SCHEMBL4477873 | 0.76 | L3MBTL1 (0.58) | TSHRL3MBTL1MAPTCBX7CDYL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |