Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | POLB | P06746 | 7/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373994 | 0.73 | CRBN (0.51) | MAPTPOLBL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL9354111 | 0.72 | ALKBH5 (0.44) | ALKBH5MAPTPOLBKMT2ATDP1 | |
| SCHEMBL10951065 | 0.70 | CES2 (0.43) | MAPTPOLBKMT2ATDP1MEN1 | |
| SCHEMBL10951060 | 0.70 | CES2 (0.43) | MAPTPOLBKMT2ATDP1MEN1 | |
| SCHEMBL8441232 | 0.67 | DAO (0.40) | MAPTKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL7175387 | 0.67 | CYP1A2 (0.42) | HSD17B10ALDH1A1SMN1; SMN2KDM4ETSHR | |
| SCHEMBL891217 | 0.66 | TSHR (0.46) | MAPTPOLBKMT2ATDP1MEN1 | |
| SCHEMBL140950 | 0.66 | TSHR (0.59) | MAPTPOLBKMT2ATDP1MEN1 | |
| SCHEMBL10981644 | 0.66 | TSHR (0.41) | MAPTPOLBKMT2ATDP1MEN1 | |
| SCHEMBL4056038 | 0.65 | GAA (0.54) | MAPTPOLBKMT2ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |