Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MLYCD | O95822 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21785057 | 0.85 | OPRM1 (0.49) | SMN1; SMN2TSHRALDH1A1GLALTB4R2 | |
| SCHEMBL8443789 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRALDH1A1GLALTB4R2 | |
| SCHEMBL16110560 | 0.82 | MEN1 (0.44) | TSHRALDH1A1GLATDP1MLYCD | |
| SCHEMBL8439833 | 0.82 | NPC1 (0.46) | SMN1; SMN2TSHRALDH1A1GLALTB4R2 | |
| SCHEMBL3138023 | 0.81 | ALDH1A1 (0.66) | SMN1; SMN2TSHRALDH1A1GLAMAPT | |
| SCHEMBL5045338 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2TSHRALDH1A1GLAMAPK1 | |
| SCHEMBL20964605 | 0.79 | LTB4R2 (0.45) | SMN1; SMN2TSHRALDH1A1GLALTB4R2 | |
| SCHEMBL5045325 | 0.78 | ALDH1A1 (0.46) | SMN1; SMN2TSHRALDH1A1GLALTB4R2 | |
| SCHEMBL8552126 | 0.78 | POLQ (0.48) | PTPN1KDM4EGAAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28795770 | 0.76 | ALDH1A1 (0.44) | SMN1; SMN2TSHRALDH1A1GLAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |
| EP-0672037-A1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| CN-1093085-A | Sulfonamide derivatives | GLAXO GROUP LTD (GB) | 1994-10-05 | — | — | CN | disclosed |
| WO-1994013648-A1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |