Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RNF4 | P78317 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21785057 | 0.85 | OPRM1 (0.49) | SMN1; SMN2ALDH1A1HTTGLATSHR | |
| SCHEMBL8443789 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HTTGLATSHR | |
| SCHEMBL8553241 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1HTTGLATSHR | |
| SCHEMBL2032136 | 0.81 | NPC1 (0.66) | NPC1RAB9APAX8JAK2SMN1; SMN2 | |
| SCHEMBL24795106 | 0.81 | MLYCD (0.49) | NPC1RAB9APAX8JAK2SMN1; SMN2 | |
| SCHEMBL5045338 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1HTTGLATSHR | |
| SCHEMBL22289656 | 0.79 | NPC1 (0.42) | NPC1RAB9APAX8JAK2SMN1; SMN2 | |
| SCHEMBL20964605 | 0.79 | LTB4R2 (0.45) | SMN1; SMN2ALDH1A1GLATSHRPOLB | |
| SCHEMBL27580163 | 0.78 | RAB9A (0.41) | NPC1RAB9APAX8JAK2SMN1; SMN2 | |
| SCHEMBL11870580 | 0.78 | ALDH1A1 (0.46) | NPC1RAB9APAX8JAK2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626380-B1 | N-(4-Fluorophenyl)-heteroaryloxyacetamide as herbicides | BAYER AG (DE) | 1999-01-13 | — | — | EP | disclosed |
| EP-0626380-A1 | N-(4-Fluorophenyl)-heteroaryloxyacetamide as herbicides | BAYER AG (DE) | 1994-11-30 | — | — | EP | disclosed |