Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556342 | 0.83 | PTGS2 (0.72) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL8554553 | 0.81 | PTGS2 (0.66) | PTGS1PTGS2GAAFPR1LMNA | |
| SCHEMBL8554850 | 0.79 | PTGS2 (0.53) | PTGS1PTGS2ALDH1A1KDM4EFPR1 | |
| SCHEMBL8552699 | 0.79 | PTGS1 (0.55) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL8552523 | 0.79 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1KDM4EFPR1 | |
| SCHEMBL8550834 | 0.79 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1MAPTFPR1 | |
| SCHEMBL8553129 | 0.79 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1FPR1SMN1; SMN2 | |
| SCHEMBL8554538 | 0.79 | PTGS1 (0.54) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL8557299 | 0.77 | PTGS1 (0.53) | PTGS1PTGS2ALDH1A1KDM4ETP53 | |
| SCHEMBL8555161 | 0.77 | PTGS2 (0.53) | PTGS1PTGS2ALDH1A1KDM4EFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |