Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552167 | 0.95 | HRH3 (0.42) | HRH3DRD2SIGMAR1DRD3 | |
| SCHEMBL8552527 | 0.89 | HRH3 (0.41) | HRH3DRD2SIGMAR1HTR2CDRD3 | |
| SCHEMBL8551063 | 0.89 | HTR2A (0.41) | HRH3MEN1KMT2ASIGMAR1HTR2A | |
| SCHEMBL8438564 | 0.87 | GSK3A (0.43) | MEN1KMT2ASIGMAR1USP2 | |
| SCHEMBL8552347 | 0.86 | LTA4H (0.41) | MEN1KMT2A | |
| SCHEMBL8440233 | 0.86 | FAAH (0.44) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL8442979 | 0.85 | GSK3A (0.46) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL8443375 | 0.84 | GAA (0.44) | HRH3MEN1KMT2AUSP2 | |
| SCHEMBL8556122 | 0.82 | USP2 (0.42) | MEN1KMT2AUSP2 | |
| SCHEMBL8772537 | 0.79 | POLB (0.40) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |