Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11088727 | 0.91 | ALDH1A1 (0.45) | POLBSMN1; SMN2ALDH1A1THRBATM | |
| SCHEMBL13174685 | 0.90 | POLB (0.48) | POLBLMNASMN1; SMN2ALDH1A1THRB | |
| SCHEMBL8554245 | 0.88 | POLB (0.43) | POLBLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL4200215 | 0.86 | POLB (0.46) | POLBLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL8324568 | 0.85 | POLB (0.50) | POLBLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29812927 | 0.84 | SMN1; SMN2 (0.49) | POLBLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL13174683 | 0.84 | POLB (0.52) | POLBLMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4599962 | 0.84 | SMN1; SMN2 (0.49) | POLBLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30089091 | 0.83 | POLB (0.48) | POLBLMNASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL2125428 | 0.83 | POLB (0.48) | POLBLMNASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |