Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417255 | 0.86 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19PDK2ALDH1A1 | |
| SCHEMBL8237704 | 0.79 | SMN1; SMN2 (0.48) | ALDH1A1KMT2AGAAGFERRECQL | |
| SCHEMBL167112 | 0.71 | MMP9 (0.51) | PDK2ALDH1A1KMT2AGAAGFER | |
| SCHEMBL27649299 | 0.71 | HSD17B1 (0.51) | ALDH1A1KMT2AGAAGFERCYP4F2 | |
| SCHEMBL6289649 | 0.69 | KMT2A (0.51) | ALDH1A1KMT2AGAAMEN1SMN1; SMN2 | |
| SCHEMBL4842048 | 0.69 | CA5A (0.58) | CYP1A2CYP2C19PDK2ALDH1A1KMT2A | |
| SCHEMBL2127345 | 0.69 | CYP4F2 (0.43) | PDK2ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL30154424 | 0.69 | CYP4F2 (0.43) | PDK2ALDH1A1GAAGFERCYP4F2 | |
| SCHEMBL5738807 | 0.69 | CA5A (0.51) | CYP1A2CYP2C19PDK2ALDH1A1KMT2A | |
| SCHEMBL2126108 | 0.69 | CYP4F2 (0.43) | PDK2ALDH1A1GAAGFERCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |