Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552803 | 0.88 | KDM1A (0.45) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL8556154 | 0.83 | DRD2 (0.48) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL12859659 | 0.79 | PRCP (0.71) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL8556491 | 0.79 | PRCP (0.71) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL28933494 | 0.79 | DRD2 (0.74) | KDM4EMAPTPKMMEN1KMT2A | |
| Bromide SCHEMBL5899013 | 0.78 | DRD2 (0.72) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL8558905 | 0.76 | TBXA2R (0.59) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL21328333 | 0.75 | BCHE (0.72) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL10348908 | 0.73 | MEN1 (0.69) | KDM4EMAPTPKMMEN1KMT2A | |
| SCHEMBL31668822 | 0.72 | BCHE (0.65) | KDM4EMAPTPKMBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |