Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.71 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.71 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12859659 | 1.00 | PRCP (0.71) | PRCPSLC22A1GID4OPRM1OPRK1 | |
| SCHEMBL8557351 | 0.88 | PRCP (0.65) | PRCPSLC22A1GID4OPRM1OPRK1 | |
| SCHEMBL9411283 | 0.86 | GID4 (0.59) | PRCPSLC22A1GID4OPRM1OPRK1 | |
| SCHEMBL8559156 | 0.85 | PRCP (0.66) | PRCPSLC22A1GID4OPRM1OPRK1 | |
| SCHEMBL10348907 | 0.84 | SLC22A1 (0.63) | PRCPSLC22A1BCHEKDM4EMAPT | |
| SCHEMBL8554897 | 0.84 | SLC22A1 (0.63) | PRCPSLC22A1BCHEKDM4EMAPT | |
| SCHEMBL4024647 | 0.84 | SLC22A1 (0.63) | PRCPSLC22A1BCHEKDM4EMAPT | |
| SCHEMBL5284097 | 0.84 | PRCP (1.00) | PRCPSLC22A1OPRM1KDM4E | |
| SCHEMBL4160731 | 0.84 | PRCP (1.00) | PRCPSLC22A1OPRM1KDM4E | |
| SCHEMBL5812041 | 0.84 | PRCP (1.00) | PRCPSLC22A1OPRM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0617022-A1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |