Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553841 | 0.88 | KDM4E (0.50) | KMT2AKDM4EMAPTPKMMEN1 | |
| SCHEMBL9411283 | 0.80 | GID4 (0.59) | OPRM1OPRK1GID4ADRA1DADRA1A | |
| SCHEMBL8982764 | 0.77 | TBXA2R (0.49) | OPRM1KMT2AKDM4EMAPTPKM | |
| SCHEMBL7744268 | 0.73 | GRIN2B (0.47) | OPRM1KMT2AMEN1 | |
| SCHEMBL6392691 | 0.73 | KMT2A (0.70) | KMT2A | |
| SCHEMBL1364325 | 0.72 | TSHR (0.41) | KMT2AMAPTPOLB | |
| SCHEMBL8556154 | 0.71 | DRD2 (0.48) | KDM1AOPRM1OPRK1KMT2AKDM4E | |
| SCHEMBL1363422 | 0.71 | KMT2A (0.39) | KMT2AMEN1POLB | |
| SCHEMBL12635434 | 0.70 | SLC6A3 (0.55) | KDM1AKMT2A | |
| SCHEMBL6392485 | 0.70 | KDM4C (0.49) | KMT2AKDM4EMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |