Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | KDM1A | O60341 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553841 | 0.83 | KDM4E (0.50) | ADRB2MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9411161 | 0.77 | PRCP (0.77) | DRD2DRD4KDM1AADRB2SLC22A1 | |
| SCHEMBL5691995 | 0.71 | PRCP (0.63) | KDM1AADRB2SLC22A1PRCP | |
| SCHEMBL28308200 | 0.71 | DRD3 (0.44) | DRD2KDM1A | |
| Bromide SCHEMBL9530444 | 0.71 | OPRM1 (0.41) | DRD2ADRB2OPRM1 | |
| SCHEMBL9126409 | 0.71 | TBXA2R (0.64) | ADRB2TBXA2ROPRM1KDM4EMAPT | |
| SCHEMBL8552803 | 0.71 | KDM1A (0.45) | KDM1AMEN1KMT2AOPRM1OPRK1 | |
| SCHEMBL27959648 | 0.70 | SLC22A1 (0.57) | KDM1AADRB2SLC22A1PRCPOPRM1 | |
| SCHEMBL27644915 | 0.70 | DRD3 (0.46) | DRD2KDM1A | |
| SCHEMBL10728169 | 0.69 | PRCP (0.77) | DRD2DRD4KDM1AADRB2SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |