Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.47 |
| ▸ | KAT6A | Q92794 | 5/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FABP1 | P07148 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556035 | 0.89 | MEN1 (0.45) | MEN1KMT2ANR4A2GPBAR1BCL2L1 | |
| SCHEMBL8553642 | 0.88 | AR (0.46) | MEN1KMT2ABCL2L1MCL1NPC1 | |
| SCHEMBL8559014 | 0.86 | MAPT (0.48) | RAB9A | |
| SCHEMBL8556744 | 0.86 | GRM5 (0.44) | KAT6A | |
| SCHEMBL9025890 | 0.85 | AR (0.45) | MEN1KMT2ANR4A2KAT6ABCL2L1 | |
| SCHEMBL8558557 | 0.84 | MEN1 (0.48) | MEN1KMT2ANR4A2KAT6AGPBAR1 | |
| SCHEMBL9025133 | 0.82 | AR (0.46) | BCL2L1MCL1NPC1RAB9AALDH1A1 | |
| SCHEMBL8558890 | 0.81 | CCR2 (0.41) | KMT2AVDRACLYNPC1ALDH1A1 | |
| SCHEMBL8557997 | 0.81 | AR (0.51) | MEN1KMT2ABCL2L1MCL1NPC1 | |
| SCHEMBL8557266 | 0.81 | AR (0.51) | MEN1KMT2ABCL2L1MCL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |