Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 8/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555239 | 0.85 | MAPT (0.48) | NPC1MAPTALDH1A1KMT2A | |
| SCHEMBL8555993 | 0.85 | HPGD (0.46) | MAPTALDH1A1 | |
| SCHEMBL8553642 | 0.83 | AR (0.46) | NPC1MAPTALDH1A1KMT2A | |
| SCHEMBL8556035 | 0.83 | MEN1 (0.45) | KMT2A | |
| SCHEMBL8555566 | 0.83 | CCR2 (0.41) | CCR2VDRCCR1APEX1ACLY | |
| SCHEMBL9025890 | 0.81 | AR (0.45) | KMT2A | |
| SCHEMBL8557997 | 0.81 | AR (0.51) | NPC1MAPTKMT2A | |
| SCHEMBL8553921 | 0.81 | MEN1 (0.48) | VDRACLYNPC1ALDH1A1KMT2A | |
| SCHEMBL8557266 | 0.79 | AR (0.51) | MAPTKMT2A | |
| SCHEMBL8560966 | 0.79 | AR (0.48) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |