Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 13/20 | 0.42 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | EIF4E | P06730 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552049 | 0.85 | SMYD3 (0.43) | — | |
| Bromide SCHEMBL8554036 | 0.80 | GSK3B (0.42) | GSK3BHTR4EP300 | |
| SCHEMBL8553962 | 0.77 | ITGB3 (0.34) | PLAT | |
| SCHEMBL8555209 | 0.77 | KDM4E (0.36) | PLAT | |
| SCHEMBL8552893 | 0.74 | SMYD3 (0.43) | — | |
| Hydrochloric Acid SCHEMBL8551719 | 0.73 | SMYD3 (0.42) | — | |
| SCHEMBL8625016 | 0.72 | KDM4E (0.49) | HTR4 | |
| Hydrochloric Acid SCHEMBL8552279 | 0.71 | MEN1 (0.38) | HTR4EIF4EMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL8549592 | 0.70 | GSK3B (0.40) | GSK3BHTR4EP300KCNH2CACNA1I | |
| SCHEMBL8550362 | 0.70 | SMYD3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |