Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.34 |
| ▸ | CCR5 | P51681 | 4/20 | 0.33 |
| ▸ | PLAT | P00750 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | CCR3 | P51677 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8551774 | 0.80 | ITGB3 (0.34) | ITGB3ITGA2BPLAT | |
| Hydrochloric Acid SCHEMBL8624199 | 0.80 | ITGB3 (0.34) | ITGB3ITGA2BPLAT | |
| SCHEMBL8552049 | 0.78 | SMYD3 (0.43) | SIGMAR1 | |
| SCHEMBL8553958 | 0.77 | GSK3B (0.42) | PLAT | |
| Hydrochloric Acid SCHEMBL8627087 | 0.73 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8627089 | 0.73 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL8551719 | 0.69 | SMYD3 (0.42) | SIGMAR1 | |
| SCHEMBL8552893 | 0.68 | SMYD3 (0.43) | ITGB3ITGA2B | |
| SCHEMBL8555209 | 0.66 | KDM4E (0.36) | PLAT | |
| SCHEMBL31706753 | 0.66 | ALDH1A1 (0.44) | PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |