Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | HTR1A | P08908 | 6/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | HTR6 | P50406 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555865 | 1.00 | HTR7 (0.61) | HTR7HTR1ASLC6A4HTR6KCNH2 | |
| SCHEMBL8558104 | 0.97 | SLC6A4 (0.61) | HTR7HTR1ASLC6A4HTR6KCNH2 | |
| SCHEMBL8560281 | 0.97 | SLC6A4 (0.61) | HTR7HTR1ASLC6A4HTR6KCNH2 | |
| SCHEMBL8554305 | 0.92 | HTR7 (0.70) | HTR7HTR1AHTR6 | |
| SCHEMBL8557189 | 0.90 | HTR6 (0.64) | HTR1AHTR6KCNH2 | |
| SCHEMBL8554971 | 0.89 | HTR7 (0.66) | HTR7 | |
| SCHEMBL8556927 | 0.88 | HTR7 (0.68) | HTR7HTR1ASLC6A4KCNH2 | |
| SCHEMBL8553986 | 0.87 | HTR6 (0.64) | HTR1AHTR6KCNH2 | |
| SCHEMBL8872143 | 0.87 | HTR1A (0.57) | HTR7HTR1ASLC6A4HTR6KCNH2 | |
| SCHEMBL8557457 | 0.86 | HTR7 (0.65) | HTR7HTR1ASLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0683166-B1 | 3-Indolylpiperidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | claimed |
| US-5693655-A | 3-indolylpiperidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-02 | — | — | US | claimed |
| EP-0683166-A1 | 3-Indolylpiperidines | MERCK PATENT GmbH (DE) | 1995-11-22 | — | — | EP | claimed |
| EP-0683166-B1 | 3-Indolylpiperidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| EP-0683166-A1 | 3-Indolylpiperidines | MERCK PATENT GmbH (DE) | 1995-11-22 | — | — | EP | disclosed |