Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553162 | 0.84 | GAA (0.45) | GAAMEN1KMT2AKDM4EUSP7 | |
| SCHEMBL8559433 | 0.81 | LRRK2 (0.46) | GAAMEN1KMT2AKDM4ENTRK1 | |
| SCHEMBL8553146 | 0.79 | NTRK1 (0.54) | KDM4ENTRK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2546236 | 0.79 | GAA (0.68) | GAAMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8554342 | 0.78 | NTRK1 (0.51) | GAAMEN1KMT2AKDM4ENTRK1 | |
| SCHEMBL8555685 | 0.78 | KDM4E (0.46) | GAAMEN1KMT2AKDM4ENTRK1 | |
| SCHEMBL27830393 | 0.78 | GAA (0.50) | GAAMEN1KMT2AKDM4EUSP7 | |
| SCHEMBL14369639 | 0.76 | CA1 (0.57) | GAAMEN1KMT2AKDM4EUSP7 | |
| SCHEMBL1800187 | 0.76 | SMN1; SMN2 (0.64) | GAAMEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL8551653 | 0.76 | NTRK1 (0.53) | KDM4ENTRK1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |