Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FPR1 | P21462 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557247 | 0.86 | NTRK1 (0.51) | NTRK1KDM4EPOLBAPEX1TDP1 | |
| SCHEMBL8550650 | 0.86 | FPR1 (0.53) | NTRK1KDM4EPOLBFPR1ALDH1A1 | |
| SCHEMBL8555862 | 0.84 | NTRK1 (0.48) | NTRK1KDM4EPOLBFPR1ALDH1A1 | |
| SCHEMBL1984012 | 0.84 | NTRK1 (0.48) | NTRK1POLBFPR1ALDH1A1HTT | |
| SCHEMBL8552895 | 0.82 | FPR1 (0.48) | NTRK1POLBTDP1FPR1ALDH1A1 | |
| SCHEMBL8553146 | 0.81 | NTRK1 (0.54) | NTRK1KDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL8554132 | 0.76 | GAA (0.48) | NTRK1KDM4EPOLBHPGDALDH1A1 | |
| SCHEMBL1244767 | 0.75 | PTGS2 (0.49) | NTRK1KDM4EPOLBTDP1FPR1 | |
| SCHEMBL8554704 | 0.75 | CA1 (0.43) | NTRK1KDM4EPOLBTDP1FPR1 | |
| SCHEMBL8553012 | 0.75 | LMNA (0.49) | KDM4EPOLBFPR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |