Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551653 | 0.81 | NTRK1 (0.53) | NTRK1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8554132 | 0.79 | GAA (0.48) | NTRK1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8550650 | 0.76 | FPR1 (0.53) | NTRK1ALDH1A1KDM4ELMNAHTT | |
| SCHEMBL8557247 | 0.76 | NTRK1 (0.51) | NTRK1HPGDALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8554342 | 0.76 | NTRK1 (0.51) | NTRK1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8553162 | 0.76 | GAA (0.45) | NTRK1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL1984012 | 0.75 | NTRK1 (0.48) | NTRK1ALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL8555862 | 0.75 | NTRK1 (0.48) | NTRK1ALDH1A1KDM4ELMNATSHR | |
| SCHEMBL8559433 | 0.74 | LRRK2 (0.46) | NTRK1HPGDALDH1A1KDM4ELMNA | |
| SCHEMBL8552895 | 0.73 | FPR1 (0.48) | NTRK1ALDH1A1LMNASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |